Biosynthetic Sesame Oil and Nano Titanium Dioxide As a Therapy For Second Degree Burns

Abstract

As  the healing of burn wounds delay that affect the skin and lead to tearing and damage to its parts, as well as the remaining traces and scars on the skin because of exposure to heat, radiation, radioactivity, electricity, friction, or contact with chemicals, it has become necessary to investigate and discover effective medicines. Burns that affect the skin have an important purpose, Therefore, it is important to continue studying and experimenting with new and effective medicines, including effective nanomaterials, to reach efficient treatments to treat such injuries. In the current study, nanoparticles of titanium dioxide (TiO2) were prepared, and this material was examined using a device a Field Emission Electron Scanning Microscope (FE-SEM). The results obtained were on the nanoscale, with sizes ranging from (31.52-69.08) nanometers. The effectiveness and effect of biosynthetic nanomaterials and sesame seeds were investigated in vivo at a concentration of 1% TiO2 and 20% sesame oil on burns in the skin of laboratory rats and compared with a control group of natural skin of the same type of laboratory rats. They were also compared with rats treated with Mebo ointment. Randomly, 18 rats were put into three equal groups and treated once daily for 28 days. The results of the study showed effective activity and a noticeable speed in the healing of burns that affected the skin of laboratory rats using a nano-titanium dioxide preparation supported by sesame seed extract whose burn mean amounted to 0.005 compared to the control treatment, whose burn mean was 2.443. According to the current study's findings, using biosynthetic nano-titanium dioxide and sesame oil together results in better burn wound healing than using each of them separately.