Characteristics of Lactobacillus Spp. Isolated From the Infant’s Feces As a Potential Probiotic in Vitro

Abstract

This study aimed to identify and characterize the potential probiotic Lactobacillus spp isolated from healthy newborns' feces and assessed in vitro. This study examined the strain for resistance to (pH 2, 3 h), and antimicrobial activities against some human pathogenic strains (Escherichia coli and Staphylococcus aureus) of thirty positive isolates were assessed. Lactobacillus spp. showed tolerance properties to acid conditions Furthermore, they exhibited survival at pH 2 in the existence of pepsin. Using the well-diffusion method, all strains demonstrated potent antibacterial activity against enteropathogens. Furthermore, cell-free culture supernatants with low pH had great antimicrobial activity and displayed this effect against S. aureus more than the effect against E,coli only as a result. Thus, the thirty Lactobacillus strains could be considered as potential probiotics, but further in vitro and in vivo studies on these probiotic strains are still required.