Comparison Of Serum Galectin-13, Aldosterone And Electrolytes (NA+, K+, CL-) In Preeclamptic And Healthy Pregnant Women

Abstract

Preeclampsia is recognized as a vascular disorder of pregnancy with poorly developed placenta leading to reduced perfusion and ischemia. Its incidence is increased by 25% during last two decades. Total 108 pregnant women were enrolled in our research divided in two groups. Blood samples were taken at 36-40 weeks of gestation and were processed and stored for galectin-13, aldosterone and electrolytes (Na⁺, K⁺, Cl^-) measurement. Data was analyzed by SPSS. We observed that Galectin-13 levels were non significantly decreased while aldosterone levels were significantly reduced, the electrolytes, sodium and chloride were found significantly increased, and potassium was significantly decreased. Galectin-13 was found to be positively correlated with aldosterone suggesting potential role of these novel hormones in pathogenesis of preeclampsia. Raised sodium and chloride while reduced potassium have significant role in development of preeclampsia.