Plasma Fibrinogen Level’s: A Comparative Study Between Newly Diagnosed Diabetics and Healthy Individuals

Abstract

The study examines the plasma fibrinogen levels in patients with newly diagnosed Type 2 Diabetes Mellitus (T2DM) compared to healthy individuals at Aarupadai Veedu Medical College in Puducherry. Plasma fibrinogen, an essential protein involved in the process of blood clotting, also functions as a biomarker for cardiovascular and inflammatory illnesses. Employing a comparative cross-sectional approach, we assessed the levels of fibrinogen in a group of 57 patients with newly diagnosed type 2 diabetes mellitus (T2DM) and a group of 57 healthy individuals who were in non-diabetic. The findings indicate a substantial increase in fibrinogen levels among individuals with newly diagnosed type 2 diabetes mellitus (T2DM) at 384.66 mg/dL, in contrast to the control group at 287.24 mg/dL, with a p-value of less than 0.0001. The age distribution discrepancies were found to be statistically significant (p=0.007), indicating that age may be a confounding factor. The gender distribution was balanced, suggesting the absence of any gender-related prejudice. The results of our study emphasise the increased levels of fibrinogen in patients with newly diagnosed type 2 diabetes mellitus (T2DM) and emphasise the necessity for additional investigation into its clinical significance and potential as a target for therapy.