An Overview of the Osteogenic potential of Indian herb Cissus quadrangularis (Veldt Grape)

Abstract

Cissus quadrangularis (CQ) is a widely known herb in India and southern part of India in particular. The bone healing ability of CQ is outlined in Ayurvedic medicine and other ancient medical texts. Bone loss in elderly especially osteoporosis is a public health problem across the globe. Bioactive molecules present in medicinal plants like CQ helps not only in bone healing but also in improving overall health. CQ is suggested as a plant herb in treatment of bone fractures and bone loss as it is safe or usage and side effects are not identified so far.
However, research on the effect of CQ in humans are few and far. This review attempts to give a clear picture on the available literature that describes the osteogenic role of CQ in improving bone health and healing fractures in general and maxillofacial fractures in particular. Also, the role of CQ in green synthesis of bone scaffolds and its osteogenic potential in regeneration of bone using scaffolds are also discussed.