Chemical Modification and Pharmaceutical Evaluation of Starch obtained from Edible Natural Sources

Abstract

This study investigates the carboxymethylation of starch extracted from Echinochloa esculenta and Lens culinaris, aiming to characterize their properties and evaluate their pharmaceutical potential. Fourier Transform Infrared Spectroscopy (FTIR) confirmed successful carboxymethylation, with characteristic peaks at 3399.47 cm⁻¹ to 3402.81 cm⁻¹ for Echinochloa esculenta and Lens culinaris respectively. Similarly, succinylation chemical modifications of starches were carried out for Echinochloa esculenta and Lens culinaris. Wound healing dressings were prepared from these succinylated starches, impregnated with giloy and turmeric extract. In vivo evaluation using albino rats showed a 30% faster wound closure compared to controls, demonstrating significant potential in therapeutic applications. This application on animal is the result of wound healing management by modified starch.