GLIOBLASTOMA: A CLINICAL CASE STUDY

Abstract

Glioblastoma is a rapidly progressing tumor with a poor prognosis, marked by a 5-year survival rate of around 5%. Variability in survival outcomes is largely related to the tumor's molecular-genetic and histological characteristics. Despite ongoing efforts to develop new, effective treatments for glioblastoma, clinical practice still primarily involves surgery, radiotherapy, and chemotherapy, along with symptomatic treatment (anticonvulsants, anti-edema medications). Nevertheless, within the current clinical paradigm, optimal outcomes can be achieved by analyzing diagnostic and therapeutic errors.
The objective of this publication is to investigate ways to improve glioblastoma treatment outcomes through a clinical case study of a female patient with glioblastoma, tonic-clonic seizures, traumatic brain injury, residual encephalopathy, and left eye strabismus.
Materials and Methods
We present a clinical case involving a female patient born in 1988 who was diagnosed with glioblastoma in December 2019.
Results
The diagnosis of “glioblastoma” was made a year and three months after the onset of tonic-clonic seizures. Despite intensive treatment, the patient passed away in December 2019 due to the progression of recurrent tumor.
Conclusion
In patients with sudden onset of epileptic seizures, a history of traumatic brain injury, and uncorrectable vision impairment, oncological screening should be conducted. Early diagnosis can increase survival rates for patients with glioblastoma.