Calcium Regulation And The Medical Advantages Of Vitamin K2

Abstract

Vitamin K2, particularly in the menaquinone forms (MK-4 and MK-7), is a critical nutrient for calcium regulation, ensuring its proper utilization in bones and prevention of vascular calcification. This review explores the molecular mechanisms of Vitamin K2, its unique advantages over Vitamin K1, and its role in bone and cardiovascular health. Traditional and cultural sources of Vitamin K2, such as natto, fermented dairy products, and animal-derived foods, are highlighted for their contributions to global diets. The interplay between Vitamin K2 and Vitamin D, as well as emerging clinical research, underscores its therapeutic potential. Future studies focusing on long-term supplementation, synergy with other nutrients, and broader metabolic benefits are essential for unlocking the full potential of Vitamin K2 in promoting health and preventing disease.