Phytochemical and Pharmacological Evaluation of Andrographis Paniculata and AdhatodaVasaka

Abstract

This prospective study researching the phytochemical and phytochemical properties of AndrographisPaniculata and AdhatodaVasaka, which are well known medicinal plants. The leaves of both plants were subsequently prepared into methanolic extracts and screened for phytochemicals such as alkaloids, flavonoids, terpenoids, saponins, tannins and glycosides. The antibacterial activity of both extracts was strongly shown, AndrographisPaniculata inhibits Staphylococcus aureus while AdhatodaVasaka is more effective in Escherichia coli. The ability of Andrographis Paniculata to possess anti-inflammatory activity was evaluated by measuring its effect on the carrageenan induced paw oedema model in Rhythas. Free radical scavenging activity was assessed by the DPPH assay using Andrographis Paniculata having stronger antioxidant potential than Datura stramonium. Both extracts were discovered to be nontoxic at high doses. These results offer promise that both plants might have pharmacological value in infections, inflammation and oxidative stress treatments but further research is required to clarify how.