COMPARISON OF INTRAPERITONEAL INSTILLATION OF BUPIVACAINE (0.5%) WITH TRAMADOL VERSUS ROPIVACAINE (0.5%) WITH TRAMADOL FOR POST OPERATIVE ANALGESIA AFTER LAPAROSCOPIC CHOLECYSTECTOMY: RANDOMIZED DOUBLE BLIND CLINICAL STUDY

Abstract

Introduction: Laparoscopic cholecystectomy, a common surgical procedure for gallbladder removal, offers less postoperative pain and quick recovery. However, acute pain often hinders Enhanced Recovery After Surgery (ERAS). Proper pain management improves patient comfort and surgical outcomes. Aims: The study evaluates Tramadol, Bupivacaine, and Ropivacaine's effectiveness in post-operative analgesia following laparoscopic cholecystectomy, comparing duration, pain severity, first rescue time, hemodynamic stability, and adverse effects. Methodology: The study compared the efficacy of Bupivacine 0.5% and Ropivacaine 0.5% for postoperative pain relief after elective laparoscopic abdominal surgeries in patients aged 18-60 with ASA physical status 1 and 2 admitted for laparoscopic cholecystectomy under general anesthesia. The study involved 72 patients, divided into two groups, and included preanesthetic checkups, rescue analgesia, and data analysis. Results: The study compared the effects of BT and RT on patients with various conditions, finding no significant differences. BT showed lower VAS score and longer-lasting analgesia. Discussion: Local anaesthetics like bupivacaine and ropivacaine are commonly used for intraperitoneal infiltration, providing effective pain management and stable hemodynamic profiles, with potential for further research. Conclusion: The study indicates that intra-peritoneal BT-Tramadol combination offers superior postoperative analgesia for 5 hours compared to RT (3 hours) with less need for rescue analgesia.