A PATIENT WITH CHRONIC MYELOID LEUKEMIA WITH MANIFESTATIONS OF LEUKOSTASIS RETINOPATHY

Abstract

Leukostasis retinopathy is a rare eye complication in chronic myeloid leukemia (CML) patients due to hyperleukocytosis. This report discusses the case of a 20-year-old man who was diagnosed with accelerated phase CML and presented with leukostasis retinopathy with symptoms of blurred vision and diplopia. Funduscopic examination revealed retinal hemorrhage, vascular tortuosity, and venous dilatation, which is typical of leukostasis retinopathy secondary to hyperleukocytosis. Supportive therapy was provided in the form of rehydration, correction of hyperuricemia and hyperkalemia, as well as cytoreductive agents imatinib and hydroxyurea, which resulted in significant clinical improvement. This report highlights the importance of early diagnosis and aggressive treatment of leukostasis retinopathy to prevent serious complications.