Effect Of Intracanal Cryotreated 2% Chlorhexidine on Postoperative Pain After Following Root Canal Treatment- A Randomized Controlled Clinical Trial

Abstract

This randomized controlled clinical trial evaluates the effectiveness of cryotreated 2% chlorhexidine (CHX) in reducing postoperative pain following root canal treatment (RCT). By combining CHX’s antimicrobial properties with the anti-inflammatory benefits of cryotherapy, this study aimed to address the common issue of pain after RCT. Forty participants were divided into two groups: one receiving standard 2% CHX and the other cryotreated 2% CHX at 2°C–4°C. Pain levels were assessed using a visual analog scale (VAS) at 24, 48, and 72 hours post-treatment. The results demonstrated significantly lower pain scores in the cryotreated group (mean VAS: 2.10 ± 0.30) compared to the standard CHX group (mean VAS: 5.20 ± 0.40) with P < 0.05. These findings highlight the potential of cryotreated CHX as an effective intracanal irrigant for enhancing patient comfort and improving recovery after endodontic procedures. Further research is recommended to refine its clinical applications.