Comparative Evaluation of Chionanthus Potencies in Homeopathic Management of Gallbladder Stones: A Randomized Clinical Study

Abstract

Background: Gallbladder stones (cholelithiasis) are a common medical condition that may require invasive interventions. Homeopathy offers a potential non-invasive alternative, with Chionanthus virginicus traditionally used for gallbladder and liver conditions. This study investigates the comparative efficacy of Chionanthus 200C and 50M potencies in managing gallbladder stones and associated symptoms.
Objective: To evaluate and compare the effects of Chionanthus 200C and 50M in reducing gallstone size and alleviating symptoms such as pain, nausea, and bloating.
Methods: A randomized trial included 60 participants diagnosed with gallstones via ultrasound imaging. Participants were divided into two groups: one treated with Chionanthus 200C and the other with Chionanthus 50M. Treatment effects were monitored at baseline, three months, and six months using ultrasound imaging and symptom assessments. Exclusion criteria included severe comorbidities, prior gallbladder surgery, and allergies to Chionanthus.
Results: Chionanthus 200C showed significant stone size reduction, with some patients achieving complete resolution of smaller stones. Symptom relief in this group was also notable, particularly for pain and nausea. Chionanthus 50M demonstrated superior symptomatic relief, including substantial reductions in pain, nausea, and bloating, though its effect on stone size was less pronounced. Gender distribution and baseline characteristics were balanced across groups.
Conclusion: Chionanthus 200C is more effective for physical stone reduction, whereas Chionanthus 50M excels in symptom management. These findings highlight the potential for individualized potency selection based on treatment goals. Further research with larger sample sizes and longer follow-up periods is recommended to validate these results and explore underlying mechanisms.