Royal Jelly Potentially Reduces Oxidative Stress and Inflammation after Physical Activity: A Systematic Literarure Review

Abstract

This study aims to analyze and highlight the potential of Royal Jelly in reducing oxidative stress and inflammation after physical activity/exercise. This study used a systematic literture review (SLR) method by searching in various journal databases such as Scopus, Pubmed, ScienceDirect, and Google Scholar. The inclusion criteria in this study were articles published within the last 15 years and articles that discussed Royal Jelly, Free Radicals, and Physical Exercise. A total of 1837 articles from the Scopus, Pubmed, ScienceDirect, and Google Scholar databases were identified. A total of 13 articles that met the inclusion criteria were selected and analyzed for this SLR. For operating standards, this study followed the PRISMA assessment. The results of this systematic research review reported that the flavonoid content found in Royal Jelly has anti-oxidant properties. In addition, Royal Jelly's anti-inflammatory properties can reduce uncontrolled inflammation caused by intense physical activity and exercise. In this case, royal jelly works by inhibiting inflammation by increasing the secretion of anti-inflammatory cytokines (interleukin-10), which show significant pro-inflammatory effects such as TNF-α. We recommend royal jelly be used in individuals to reduce oxidative stress and inflammation caused by intense physical activity and exercise.