EVALUATION OF EFFECTS OF ANTI-EPILEPTIC DRUGS ON BONE MINERAL DENSITY IN EPILEPTIC CHILDREN

Abstract

INTRODUCTION
Epilepsy is a common medical and social disorder characterized by epileptic seizures. The brain's electrical signals are disrupted, which causes these seizures. Seizures result from these disturbances, which momentarily impair nerve cell communication. Additional potential pathways include a direct impact on bone cells, such as calcitonin insufficiency, hypo-parathyroidism, and decreased calcium absorption and decreased responsiveness to parathyroid hormone. The connection between AEDs and bone disease has been explained by a number of theories. Furthermore, extending the anti-epileptic medication course may raise the risk of osteopenia and fractures.