Additive Manufacturing Excellence: A Review of 3D Printing Process in Precise Drug Delivery for Personalized Medicine

Abstract

Three-dimensional Printing (3DP), as an additive manufacturing technique, has emerged as a promising technology for the production of personalized medicine, tissue organ development, customized implants, complex drug release profile, anatomical model for surgical preparation, engineering components, setting it apart from conventional manufacturing methods. Precision medicines have acquired a foothold in the Healthcare sector pharmaceutical sector thanks. Integrating 3D Printing with AI Platform can amplify its potential by improving the customization, efficiency and safety. 3D printing involves the establishment of a three-dimensional object, in a layer upon layer manner using various computer software. Digital fabrication technology referred to as 3DP or additive manufacturing, produces physical objects by incrementally adding materials according to a geometric model. It creates new opportunities for improving efficacy, safety, and convenience of medicines. The major technological platforms of 3D printing researched on in the pharmaceutical sector include inkjet printing, binder jetting, fused filament fabrication, selective laser sintering, stereolithography, and pressure-assisted microsyringe. To broaden the applications of 3D printed components, greater emphasis should be placed on creating cost-effective printer technologies and materials that are compatible with these printers. The technology operates by sequentially depositing material from a computer-aided design (CAD) model into the production of an object. Applications of 3D printing integrated customized delivery and devices include dose personalization, multidrug composition, modified release system, medical implants, and particular demographic-specific customization. The present paper presents a comprehensive overview of various 3DP technologies, detailing their advantages, disadvantages, applications, & the materials utilized in industries like manufacturing.