Exploring Sudanese Medicinal Plants for their Antidiabetic and Hypolipidemic Benefits: A Review

Abstract

Diabetes mellitus and associated lipid disorders are major threats to the public health in the global societies and particularly in the developing countries where synthetic medications are not easily available. This review aims to determine various Sudanese medicinal plants and their effects on antidiabetic and hypolipidemic properties, which are vital parts of the research since Sudan is endowed with diverse bio and ethnomedical resources. The article conduct a systematic review of the literature in order to examine the plants that can be used to treat diabetes and lipid profile in a scientific manner. The specific phytochemicals mentioned include flavonoids, alkaloids, saponins, and polyphenols for their bioactivities. Furthermore, the ways through which the action of these drugs influence glucose homeostasis, insulin release, and lipid absorption are also reviewed. Some important findings recommend that a number of Sudanese medicinal plants have a potent antidiabetic and hypolipidemic potency, which may be a blend of flavonoids, alkaloids, and terpenoids bioactive compounds were proposed to be accountable. The data given in the review might be valuable for a comprehensive evaluation of the therapeutic efficacy of these plants as new sources of natural drugs for the treatment of diabetes and dyslipidemia and an illustration of how traditional experience might be translated into the terms of modern pharmacology. This review also recognizes research limitations calling for more rigorous clinical trials to substantiate the efficacy and safety of these medicinal plants.