MULTIMODAL MANAGEMENT OF POST-INFECTIVE NON-UNION OF HUMERAL SHAFT FRACTURE: A CASE REPORT AND LITERATURE REVIEW

Abstract

Background: Chronic humeral shaft non-union poses a challenging clinical scenario, particularly in patients with multiple comorbidities. Orthopedic infections, including osteomyelitis, present further complexities in treatment, often requiring a comprehensive approach.
Case Report: We present a case of a 62-year-old male with chronic humeral shaft non-union, complicated by previous infection and surgical intervention. Despite challenges, the patient underwent successful multimodal surgical management, including debridement, autografting, locking plate fixation, and adjunctive therapies such as the application of antibiotic-impregnated calcium sulfate beads and tricalcium phosphate granules along with parathyroid hormone therapy. Postoperative rehabilitation contributed to a satisfactory functional outcome, highlighting the importance of a comprehensive approach in managing complex orthopedic conditions.
Conclusion: This case underscores the effectiveness of a multimodal approach in managing chronic humeral shaft non-union. Despite comorbidities and previous complications, surgical intervention coupled with adjunctive therapies can lead to favorable outcomes and restoration of function in selected patients.