Epidemiology of Primary Brain Tumors in Anatomical Pathology Laboratory at National Brain Center Prof. Dr. dr. Mahar Mardjono Hospital Jakarta on 2021-2022

Abstract

Brain neoplasms constitute an infrequent pathology with a relatively low prevalence; nevertheless, they are associated with a noteworthy fatality rate. The aggregate occurrence of primary brain neoplasms is estimated at approximately 7 per 100,000 individuals per annum, representing merely 1.4% of all malignancies. The primary intent of this investigation is to delineate the descriptive epidemiology of brain neoplasms as observed within the Anatomical Pathology Laboratory at the National Brain Center (NBC) Prof. Dr. dr. Mahar Mardjono Hospital, Jakarta, spanning the years 2021 to 2022. This inquiry employs a descriptive epidemiological approach, utilizing medical archives of individuals diagnosed with primary brain neoplasms throughout the 2021–2022 period at the Anatomical Pathology Laboratory of NBC Prof. Dr. dr. Mahar Mardjono Hospital, Jakarta. The data encompasses demographic attributes alongside clinical parameters, including neoplasm localization and classification. A cumulative 917 instances of primary brain neoplasms were documented (429 in 2021 and 488 in 2022). Of these, 41.6% (44.1% in 2021 and 39.5% in 2022) were identified in male individuals, whereas 58.4% (55.9% in 2021 and 60.5% in 2022) were observed in female individuals. The apex prevalence was discerned within the 41–50-year demographic (28.8%), with a distribution of 31.5% in 2021 and 26.4% in 2022. The predominant anatomical location was supratentorial (84.5%), with 84.8% in 2021 and 84.2% in 2022. The prevailing histopathological classification was meningioma (42.7%), comprising 42.6% in 2021 and 42.8% in 2022. Meningiomas were markedly more frequent in female individuals (80.9%), with an incidence of 77.9% in 2021 and 83.6% in 2022. Metastatic occurrences constituted 8.7% of cases (8% in 2021 and 9.3% in 2022). The predominance of primary brain neoplasms is discernibly higher in female individuals, with the zenith incidence observed within the 41–50-year age bracket. Meningiomas emerge as the foremost histological subtype, predominantly localized within the supratentorial compartment.