A COMPARATIVE STUDY BETWEEN THE SIMPLIFIED REID’S COLPOSCOPIC INDEX AND THE SWEDE SCORE IN EARLY DETECTION OF CERVICAL INTRAEPITHELIAL NEOPLASIA

Abstract

ABSTRACT:

Objective: The comparative study between the simplified reid’s colposcopic index (Simplified RCI) and the swede score in early detection of cervical intraepithelial neoplasia and correlation of the findings with the histopathology reports.

Methods: In the present prospective study, 6390 women were screened by pap and VIA. Cytology and/or VIA positive women were taken for colposcopy. Colposcopic findings of 147 women were scored by Simplified RCI and Swede score; and compared. Reports and findings were correlated with histopathology reports. Data was compiled and exported in SPSS V20 for Windows for statistical analysis.

Results: In this study, at cutoff of 3 for Simplified RCI sensitivity 100%, specificity 69.70%, PPV 80.40%, and NPV 100% with accuracy of 86.49% were calculated. At cutoff of 4 for Swede score sensitivity 97.60%, specificity 60.60%, PPV 75.50%, and NPV 95.20% with accuracy of 81.08% were calculated. Simplified RCI and Swede score had good correlation with the correlation coefficient (r) 0.983; P<0.0001. AUC of ROC of both tests showed excellent performance with 0.937 for Simplified RCI and 0.936 for Swede score.

Conclusions: Simplified RCI was easier to document and to recall, which makes follow up easier. Simplified RCI scoring system is based on lesion findings of each quadrant separately, so severity of lesion not affected by size.