Comparative Evaluation of Mouth Rinsing with Probiotic, Herbal, and Chlorhexidine Mouthwash on Salivary pH of Children: A Randomized Control Trial

Abstract

BACKGROUND: Maintaining an optimal salivary pH is essential for pediatric oral health to prevent dental caries and other oral diseases. Mouthwashes like Probiotic and Grape Seed Extract (GSE) are emerging as safer alternatives to traditional Chlorhexidine mouthwash.

OBJECTIVE: To compare the efficacy of probiotics, grape seed extract, and chlorhexidine mouthwashes on salivary pH in children aged 6 to 11 years.

DESIGN: A randomized controlled trial (RCT) was conducted.

SETTING: Private Dental Institute

PATIENTS AND METHODS: Thirty-six children aged 6 to 11 years were randomized into three groups: Group A: Probiotic mouthwash Group B: Grape Seed Extract mouthwash Group C: Chlorhexidine mouthwash Salivary pH was measured using a digital pH meter at baseline (day 1) and after one week (day 7) of daily use. Data were analyzed using one way ANOVA and Tukey’s post hoc test.

MAIN OUTCOME MEASURES: Change in salivary pH from baseline to day 7. SAMPLE SIZE: Thirty-six children aged 6 to 11 years RESULTS: The mean salivary pH was comparable at baseline. After one-week, probiotic mouthwash significantly increased salivary pH compared to GSE and chlorhexidine. Overall, differences among groups were statistically significant.

CONCLUSION: Probiotic mouthwash was most effective in increasing salivary pH, highlighting its potential as a safe alternative for pediatric oral health..