Integrative Synergy: Daily Ohm Chanting And Giloy-Jackfruit Decoction Improve Neuro-Metabolic Balance And Glucose Regulation In Diabetes–A Randomized Controlled Trial

Abstract

This randomized controlled trial investigates the synergistic effects of one-hour daily Ohm chanting and a decoction of giloy (Tinospora cordifolia) and jackfruit (Artocarpus heterophyllus) on neuro-metabolic parameters, neurotransmitter levels, antioxidant activity, blood pressure regulation, and glucose homeostasis in diabetic and non-diabetic individuals. Conducted from April 2024 to January 2025 at Aski Super Speciality Hospital, Bagalkot, India, the study enrolled 140 participants across four groups: diabetic on insulin therapy, diabetic on oral antidiabetics, diabetic on combined therapy, and non-diabetic controls. Primary outcomes included fasting, postprandial, and random glucose levels, HbA1c, lactate, superoxide dismutase (SOD), mannitol, serotonin, dopamine, and blood pressure. The intervention significantly reduced glucose levels, HbA1c, lactate, and superoxide while increasing SOD, mannitol, serotonin, and dopamine levels, alongside notable improvements in blood pressure (all p < 0.05). These findings suggest that the combined intervention enhances neuro-metabolic balance and neurotransmitter regulation, offering a cost-effective, non-invasive adjunctive therapy for diabetes management.